MRE-269 |CAS:475085-57-5 Probechem Biochemicals

Chemical Structure : MRE-269

CAS No.: 475085-57-5

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MRE-269 (ACT-333679, ACT333679)

货号: PC-46004Not For Human Use, Lab Use Only.

MRE-269 (ACT-333679) is a potent, selective IP receptor (prostaglandin I2 receptor) agonist with Ki of 20 nM.

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10 mg	￥1280	In stock
25 mg	￥1980	In stock
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生物&药学活性

MRE-269 (ACT-333679) is a potent, selective IP receptor (prostaglandin I2 receptor) agonist with Ki of 20 nM.
MRE-269 displays no significant affinity for other prostanoid receptors (Ki>2.6 uM).
MRE-269 is the activve metabolite of Selexipag (NS-304).

物理化学性质&存储条件

分子量	419.5161
分子式	C25H29N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 51 mg/mL
Chemical Name/SMILES	Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-

参考文献

1. Kuwano K, et al. J Pharmacol Exp Ther. 2007 Sep;322(3):1181-8.

2. Kuwano K, et al. J Pharmacol Exp Ther. 2008 Sep;326(3):691-9.

MRE-269 (ACT-333679, ACT333679)

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物理化学性质&存储条件

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MRE-269 (ACT-333679, ACT333679)

生物&药学活性

物理化学性质&存储条件

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