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MPO-IN-28

Chemical Structure : MPO-IN-28

CAS No.: 37836-90-1

MPO-IN-28 (Myeloperoxidase inhibitor 28)

货号: PC-60357Not For Human Use, Lab Use Only.

MPO-IN-28 is a potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MPO-IN-28 is a potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM.
MPO-IN-28 shows 100-fold selectivity over LPO.
MPO-IN-28 inhibits the growth of normal human dermal fibroblast with IC50 of 17 uM.

物理化学性质&存储条件

分子量 231.259
分子式 C11H13N5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(7-methoxy-4-methylquinazolin-2-yl)guanidine

参考文献

1. Soubhye J, et al. J Med Chem. 2017 Jul 19. doi: 10.1021/acs.jmedchem.7b00285.

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