MPC-0767 |CAS:1310540-32-9 Probechem Biochemicals

Chemical Structure : MPC-0767

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MPC-0767 (MPC 0767;MPC0767;MPC3100 mesylate hydrate)

货号: PC-60470Not For Human Use, Lab Use Only.

MPC-0767 (MPC0767, MPC3100 mesylate hydrate) is an L-alanine ester prodrug of MPC-3100, which is a potent, selective, orally bioavailable Hsp90 inhibitor with IC50 of 0.14 uM.

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生物&药学活性

MPC-0767 (MPC0767, MPC3100 mesylate hydrate) is an L-alanine ester prodrug of MPC-3100, which is a potent, selective, orally bioavailable Hsp90 inhibitor with IC50 of 0.14 uM.
MPC-0767 exhibits improved aqueous solubility, adequate chemical stability, and rapid bioconversion without the need for solubilizing excipients.

物理化学性质&存储条件

分子量	663.559
分子式	C23H31BrN6O8S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S)-1-[4-[2-[6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl]ethyl]-1-piperidinyl]-2-hydroxy-1-propanone mesylate hydrate

参考文献

1. Kim SH, et al. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5254-7.

MPC-0767 (MPC 0767;MPC0767;MPC3100 mesylate hydrate)

生物&药学活性

物理化学性质&存储条件

参考文献

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询单

MPC-0767 (MPC 0767;MPC0767;MPC3100 mesylate hydrate)

生物&药学活性

物理化学性质&存储条件

参考文献

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