Chemical Structure : MO2455
货号: PC-28601Not For Human Use, Lab Use Only.
MO2455 is a synthesized imatinib-derived compound that exert potent cytotoxic effects on leukemia cells with IC50 of 0.83 μM, 0.43 μM and 0.57 μM in U937, THP-1 and CCRF-CEM cells, promotes leukemic cell death by activating the intrinsic apoptotic pathway.
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MO2455 is a synthesized imatinib-derived compound that exert potent cytotoxic effects on leukemia cells with IC50 of 0.83 μM, 0.43 μM and 0.57 μM in U937, THP-1 and CCRF-CEM cells, promotes leukemic cell death by activating the intrinsic apoptotic pathway.
| 分子量 | 728.89 | |
| 分子式 | C39H36N8O3S2 | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
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1. Ankitha Vadi Velu, et al. Cells. 2026 Sep 30;15(19):1780.
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