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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Ezrin-MMV667492
MMV667492

Chemical Structure : MMV667492

CAS No.: 380877-02-1

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MMV667492 (MMV 667492, MMV-667492)

货号: PC-70130Not For Human Use, Lab Use Only.

MMV667492 is a novel potent Ezrin inhibitor with Kd of 29.4 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MMV667492 is a novel potent Ezrin inhibitor with Kd of 29.4 nM.
    MMV-667492 exhibits potent anti-ezrin activity in all biologic assays and has better physicochemical properties for drug-likeness than NSC305787.
    MMV-667492 is a novel antimetastatic agent for the treatment of metastatic osteosarcoma.

    物理化学性质&存储条件

    分子量 313.357
    分子式 C17H19N3O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(3-(cyclohexylamino)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-N-methylnitrous amide

    参考文献

    1. Çelik H, et al. Mol Cancer Ther. 2015 Nov;14(11):2497-507.

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