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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-PPAR-MMT-160
MMT-160

Chemical Structure : MMT-160

CAS No.: 1639059-34-9

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MMT-160 (MMT160)

货号: PC-38650Not For Human Use, Lab Use Only.

MMT-160 is a novel selective peroxisome proliferator-activated receptor γ (PPARγ) antagonist with IC50 of 0.17 uM, covalently binds to the PPARγ ligand binding domain (LBD) via Cys285.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MMT-160 is a novel selective peroxisome proliferator-activated receptor γ (PPARγ) antagonist with IC50 of 0.17 uM, covalently binds to the PPARγ ligand binding domain (LBD) via Cys285.

    物理化学性质&存储条件

    分子量 490.563
    分子式 C30H26N4O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(5-(3-phenylpropiolamido)-2-propoxybenzyl)-4-(pyrimidin-2-yl)benzamide

    参考文献

    1. Mami Yoshizawa, et al. Bioorg Med Chem Lett. 2022 May 15;64:128676.

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