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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Matrix Metalloproteinase (MMP)-MMPI-1154
MMPI-1154

Chemical Structure : MMPI-1154

CAS No.: 1382722-47-5

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MMPI-1154 (MMPI1154)

货号: PC-63509Not For Human Use, Lab Use Only.

MMPI-1154 is a small molecule MMP-2 inhibitor with IC50 of 10/6.6/13/1.8 uM for MMP1/2/9/13, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MMPI-1154 is a small molecule MMP-2 inhibitor with IC50 of 10/6.6/13/1.8 uM for MMP1/2/9/13, respectively.
    MMPI-1154 shows significant cardio-cytoprotecion, significantly decreases infarct size when applied at 1 μM in an ex vivo model for acute myocardial infarction.

    物理化学性质&存储条件

    分子量 445.494
    分子式 C26H24FN3O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(((4-(benzyloxy)benzyl)(4-fluorobenzyl)amino)methyl)-1H-imidazole-4-carboxylic acid

    参考文献

    1. Bencsik P, et al. Front Pharmacol. 2018 Apr 5;9:296.

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