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首页-抗体药物偶连体和PROTACs-ADC Cytotoxin-MMAF-OMe
MMAF-OMe

Chemical Structure : MMAF-OMe

CAS No.: 863971-12-4

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MMAF-OMe (Monomethyl auristatin F methyl ester)

货号: PC-46001Not For Human Use, Lab Use Only.

An antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin. It is linked to an antibody with high affinity to structures on cancer cells, causing MMAF to accumulate in such cells.

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5 mg ￥2800 In stock
10 mg ￥4400 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

An antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin. It is linked to an antibody with high affinity to structures on cancer cells, causing MMAF to accumulate in such cells; an ADC payload.

物理化学性质&存储条件

分子量 745.9887
分子式 C40H67N5O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO
Chemical Name/SMILES

L-Phenylalanine, N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-, methyl ester

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