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首页-抗体药物偶连体和PROTACs-ADC Cytotoxin-MMAD hydrochloride
MMAD hydrochloride

Chemical Structure : MMAD hydrochloride

CAS No.: 173441-26-4

MMAD hydrochloride (Demethyldolastatin 10 hydrochloride;Monomethylauristatin D hydrochloride;Monomethyl Dolastatin 10 hydrochloride)

货号: PC-45998Not For Human Use, Lab Use Only.

A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs)..

规格 价格 库存 数量
50 mg ¥15504.0 In stock
100 mg ¥25840 In stock

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).

物理化学性质&存储条件

分子量 807.5253
分子式 C41H67ClN6O6S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

L-Valinamide, N-methyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-, hydrochloride (1:1)

参考文献

1. Chudasama V, et al. Nat Chem. 2016 Feb;8(2):114-9.

2. Leal M, et al. Bioconjug Chem. 2015 Nov 18;26(11):2223-32.

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