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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-MLS6585
MLS6585

Chemical Structure : MLS6585

CAS No.: 389080-71-1

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MLS6585 (MLS-6585;MLS 6585)

货号: PC-35533Not For Human Use, Lab Use Only.

MLS6585 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling and increase the affinity of dopamine for the D1 receptor with low micromolar potencies.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MLS6585 is a novel positive allosteric modulator of the D1 dopamine receptor, potentiatse dopamine-stimulated G-protein- and β-arrestin-mediated signaling and increase the affinity of dopamine for the D1 receptor with low micromolar potencies.

物理化学性质&存储条件

分子量 357.472
分子式 C19H23N3O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(6-(tert-butyl)-3-carbamoyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)isonicotinamide

参考文献

1. Luderman KD, et al. Mol Pharmacol. 2018 Aug 1. pii: mol.118.113175.

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