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MLEB-1934

Chemical Structure : MLEB-1934

CAS No.:

MLEB-1934 (MLEB1934)

货号: PC-22162Not For Human Use, Lab Use Only.

MLEB-1934 is a potent bacterial DNA gyrase inhibitor with MIC of 0.25 μg/mL in MRSA, targets the allosteric pocket of the gyrase.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MLEB-1934 is a potent bacterial DNA gyrase inhibitor with MIC of 0.25 μg/mL in MRSA, targets the allosteric pocket of the gyrase.

物理化学性质&存储条件

分子量 467.54
分子式 C27H28F3N3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-N-(((6aR,9S,10aR)-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methyl)-3-(4-(trifluoromethyl)phenyl)acrylamide

参考文献

1. Shawn French, et al. Cell Rep. 2024 Apr 4;43(4):114053.

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