ML753286 ((S)-ML753286)

Chemical Structure : ML753286

CAS No.: 1699720-85-8

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货号: PC-20192Not For Human Use, Lab Use Only.

ML753286 ((S)-ML753286) is a potent, selective BCRP inhibitor with IC50 of 0.6 uM (BCRP efflux transporter), shows no activity against P-glycoprotein (P-gp), organic anion-transporting polypeptide (OATP), or major cytochrome P450s (CYPs).

规格	价格	库存
5 mg	￥4280	In stock
10 mg	￥7280	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

ML753286 ((S)-ML753286) is a potent, selective BCRP inhibitor with IC50 of 0.6 uM (BCRP efflux transporter), shows no activity against P-glycoprotein (P-gp), organic anion-transporting polypeptide (OATP), or major cytochrome P450s (CYPs).

物理化学性质&存储条件

分子量	355.44
分子式	C20H25N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S,6S,12aS)-6-isobutyl-9-methoxy-3-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione

参考文献

1. Yuexian Li, et al. Bioorg Med Chem Lett. 2016 Jan 15;26(2):551-555.