ML 604086 |CAS:850330-18-6 Probechem Biochemicals

Chemical Structure : ML 604086

CAS No.: 850330-18-6

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ML 604086 (ML604086)

货号: PC-61979Not For Human Use, Lab Use Only.

ML 604086 (ML604086) is a potent, selective CCR8 inhibitor that inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations with IC50 of 1.3 uM and 1.0 uM respectively in cellular assays.

规格	价格	库存
10 mg	￥1980	In stock
25 mg	￥3480	In stock
50 mg	￥5980	In stock
100 mg		Get quote
1 g		Get quote

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生物&药学活性

ML 604086 (ML604086) is a potent, selective CCR8 inhibitor that inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations with IC50 of 1.3 uM and 1.0 uM respectively in cellular assays.
ML 604086 displays high selectvity against a panel of 40 GPCRs, only moderately inhibits 5HT1a (30% at 10 uM).

物理化学性质&存储条件

分子量	508.637
分子式	C27H32N4O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[4-[[[(3R,4R)-1-[(2S)-2-Amino-1-oxopropyl]-3-methyl-4-piperidinyl]amino]sulfonyl]-1-naphthalenyl]-2-methylbenzamide

参考文献

1. Jenkins TJ, et al. J Med Chem. 2007 Feb 8;50(3):566-84.

2. Wang L, et al. Thorax. 2013 Jun;68(6):506-12.

ML 604086 (ML604086)

生物&药学活性

物理化学性质&存储条件

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ML 604086 (ML604086)

生物&药学活性

物理化学性质&存储条件

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