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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-ML406
ML406

Chemical Structure : ML406

CAS No.: 774589-47-8

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ML406 (ML-406)

货号: PC-62126Not For Human Use, Lab Use Only.

ML406 is a small molecule Mtb bioA (DAPA synthase) enzyme inhibitor (IC50=30 nM) that shows anti-tubercular activity, dispalys >100-fold selectivity over bioD.

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50 mg ￥2480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ML406 is a small molecule Mtb bioA (DAPA synthase) enzyme inhibitor (IC50=30 nM) that shows anti-tubercular activity, dispalys >100-fold selectivity over bioD.
ML406 exhibits WT M. tb (H37Rv) growth inhibition without biotin with an IC50 of 3.2 uM.

物理化学性质&存储条件

分子量 352.39
分子式 C20H20N2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(4-(4-(Benzo[d][1,3]dioxole-5-carbonyl)piperazin-1-yl)phenyl)ethanone

参考文献

1. Casalena D, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

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