Chemical Structure : ML402
CAS No.: 298684-44-3
货号: PC-60336Not For Human Use, Lab Use Only.
ML402 is a potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC50 of 13.7 and 5.9 uM, respectively.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥880 | In stock | |
10 mg | ¥1280 | In stock | |
25 mg | ¥1980 | In stock | |
50 mg | ¥3280 | In stock | |
100 mg | Get quote |
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ML402 is a potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC50 of 13.7 and 5.9 uM, respectively.
ML402 displays no significant activity for K2P4.1 (at 50 uM); shows insensitivity to mutant K2P2.1(K271Q), and has similar EC50 for K2P4.1(Q258K) (EC50=13.6 uM).
分子量 | 295.781 | |
分子式 | C14H14ClNO2S | |
外观性状 | Solid | |
储存条件 |
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|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
N-[2-(4-chloro-2-methylphenoxy)ethyl]thiophene-2-carboxamide |
1. Lolicato M, et al. Nature. 2017 Jul 20;547(7663):364-368.
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