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首页-小分子抑制剂&激动剂-GPCR-GPR183 (EBI2)-ML401
ML401

Chemical Structure : ML401

CAS No.: 1597489-14-9

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ML401 (CID73169083, ML-401)

货号: PC-62127Not For Human Use, Lab Use Only.

ML401 (CID73169083) is a potent, functional antagonist of EBI-2 (Epstein-Barr virus-induced gene 2, GPR183) with IC50 of 1 nM, displays activity in a chemotaxis assay (IC50=6 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ML401 (CID73169083) is a potent, functional antagonist of EBI-2 (Epstein-Barr virus-induced gene 2, GPR183) with IC50 of 1 nM, displays activity in a chemotaxis assay (IC50=6 nM).
ML401 exhibits a clean profile in a Eurofins/Ricerca panel as well as excellent rodent pharmacokinetics.
ML401 is a valuable tool to explore the in vivo effects of EBI-2 inhibition.

物理化学性质&存储条件

分子量 419.747
分子式 C20H20BrClN2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-3-(4-bromophenyl)-1-(4-(4-chlorobenzyl)-piperazin-1-yl)prop-2-en-1-one

参考文献

1. Ardecky R, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

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