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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-ML400
ML400

Chemical Structure : ML400

CAS No.: 1908414-42-5

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ML400 (ML 400;ML-400)

货号: PC-60897Not For Human Use, Lab Use Only.

ML400 is a potent, selective, allosteric LMPTP inhibitor with IC50 of 1.68 uM, displays good selective against other phosphatases.

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10 mg ￥3780 In stock
25 mg ￥5980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ML400 is a potent, selective, allosteric LMPTP inhibitor with IC50 of 1.68 uM, displays good selective against other phosphatases.
ML400 displays good cell-based activity as well as rodent pharmacokinetics.
ML400 is a valuable tool to explore the effects of selective LMPTP inhibition in vitro and in vivo.

物理化学性质&存储条件

分子量 375.516
分子式 C24H29N3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(4-methoxyphenyl)-N-(3-(piperidin-1-yl)propyl)quinolin-4-amine

参考文献

1. Stanford SM, et al. Nat Chem Biol. 2017 Jun;13(6):624-632.

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