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首页-小分子抑制剂&激动剂-Others-Protein Disulfide Isomerase (PDI)-ML359
ML359

Chemical Structure : ML359

CAS No.: 1069858-99-6

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ML359 (ML 359)

货号: PC-62115Not For Human Use, Lab Use Only.

ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM.

规格 价格 库存 数量
5 mg ￥2180 In stock
10 mg ￥3580 In stock
25 mg ￥5480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ML359 is a small molecule, specific inhibitor of Protein disulfide isomerase (PDI) with IC50 of 250 nM.
ML359 displays >100-fold selectivity over other thiol isomerases (Erp5, Thioredoxin, Thioredoxin reductase).
ML359 shows no cytotoxicity in three human cell lines, and some activity in inhibiting platelet aggregation in vitro.

物理化学性质&存储条件

分子量 417.93
分子式 C23H28ClNO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 100 mg/mL
Chemical Name/SMILES

Ethyl 1-(3-chloro-4-hydroxybenzyl)-4-(2-phenoxyethyl)piperidine-4-carboxylate

参考文献

1. Khodier C, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

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