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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-ML339
ML339

Chemical Structure : ML339

CAS No.: 2579689-83-9

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ML339 (ML 339)

货号: PC-38130Not For Human Use, Lab Use Only.

ML 339 is a potent and selective hCXCR6 antagonist (IC50 = 140 nM), 100-fold less active at the murine CXCR6 receptor (IC50 = 18 uM).

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5 mg ￥1880 In stock
10 mg ￥2980 In stock
25 mg ￥4980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ML 339 is a potent and selective hCXCR6 antagonist (IC50 = 140 nM), 100-fold less active at the murine CXCR6 receptor (IC50 = 18 uM)。
ML 339 exhibits selectivity over CXCR5, CXCR4, CCR6 and APJ receptors.

物理化学性质&存储条件

分子量 502.008
分子式 C26H32ClN3O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 1 Month
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

9-Azabicyclo[3.3.1]nonane-9-acetamide, N-(2-chlorophenyl)-3-[(3,4,5-trimethoxybenzoyl)amino]-, (3-exo)-

参考文献

1. Satyamaheshwar Peddibhotla, et al. Bioorg Med Chem Lett. 2020 Feb 15;30(4):126899.

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