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首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-ML339
ML339

Chemical Structure : ML339

CAS No.: 2080300-49-6

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ML339 (ML 339)

货号: PC-38130Not For Human Use, Lab Use Only.

ML 339 is a potent and selective hCXCR6 antagonist (IC50 = 140 nM), 100-fold less active at the murine CXCR6 receptor (IC50 = 18 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    ML 339 is a potent and selective hCXCR6 antagonist (IC50 = 140 nM), 100-fold less active at the murine CXCR6 receptor (IC50 = 18 uM)。
    ML 339 exhibits selectivity over CXCR5, CXCR4, CCR6 and APJ receptors.

    物理化学性质&存储条件

    分子量 502.008
    分子式 C26H32ClN3O5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 1 Month
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    9-Azabicyclo[3.3.1]nonane-9-acetamide, N-(2-chlorophenyl)-3-[(3,4,5-trimethoxybenzoyl)amino]-, (3-exo)-

    参考文献

    1. Satyamaheshwar Peddibhotla, et al. Bioorg Med Chem Lett. 2020 Feb 15;30(4):126899.

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