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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-MITF-ML329
ML329

Chemical Structure : ML329

CAS No.: 19992-50-8

ML329 (ML-329;ML 329)

货号: PC-42394Not For Human Use, Lab Use Only.

ML329 is a small molecule micropthalmia-associated transcription factor (MITF) that inhibits the promoter activity of a MITF target gene, melastatin (TRPM-1) with IC50 of 1.2 uM.

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5 mg ¥1280 In stock
10 mg ¥1980 In stock
25 mg ¥3280 In stock
50 mg ¥5480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ML329 is a small molecule micropthalmia-associated transcription factor (MITF) that inhibits the promoter activity of a MITF target gene, melastatin (TRPM-1) with IC50 of 1.2 uM.
ML329 shows specific activity against the MITF-dependent cells, primary melanocytes but no effect on the viability in A375 cells.

物理化学性质&存储条件

分子量 328.34248
分子式 C16H12N2O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 31 mg/mL

Chemical Name/SMILES

Benzenesulfonamide, 4-[(1,4-dihydro-1,4-dioxo-2-naphthalenyl)amino]-

参考文献

1. Faloon PW, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

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