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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-ML321
ML321

Chemical Structure : ML321

CAS No.: 1596117-75-7

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ML321 (ML 321)

货号: PC-38703Not For Human Use, Lab Use Only.

ML321, CAS 1596117-75-7, ML 321, D2R antagonist. ML321 is a selective small molecule dopamine D2 receptor (D2R) antagonist with binding Ki of 120 nM, exhibits an excellent D2 versus D1, D3, D4 and D5 receptor selectivity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    ML321 is a selective small molecule dopamine D2 receptor (D2R) antagonist with binding Ki of 120 nM, exhibits an excellent D2 versus D1, D3, D4 and D5 receptor selectivity.

    物理化学性质&存储条件

    分子量 410.506
    分子式 C21H18N2O3S2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    10-Methyl-11-oxo-N-(2-(thiophen-2-yl)ethyl)-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide 5-(S)-oxide

    参考文献

    1. Ashley N Nilson, et al. FASEB J. 2022 May;36 Suppl 1.

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