ML307 | Ubc13 inhibitor | Probechem Biochemicals

Chemical Structure : ML307

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ML307 (ML-307)

货号: PC-38264Not For Human Use, Lab Use Only.

ML307 is a potent, sub-micromolar (IC50=781 nM), first-in-class, small molecule inhibitor of Ubc13 enzyme activity, >128-fold selective against Caspase-3 and Bfl-1.

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生物&药学活性

ML307 is a potent, sub-micromolar (IC50=781 nM), first-in-class, small molecule inhibitor of Ubc13 enzyme activity, >128-fold selective against Caspase-3 and Bfl-1.

物理化学性质&存储条件

分子量	522.094
分子式	C28H36ClN7O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-((1-(3-chlorobenzyl)piperidin-4-yl)methyl)-1-(6,7,8,9-tetrahydropyrido[1,2-e]purin-4-yl)piperidine-3-carboxamide

参考文献

1. Robert Ardecky, et al. Probe Reports from the NIH Molecular Libraries Program [Internet]. 2012.

ML307 (ML-307)

生物&药学活性

物理化学性质&存储条件

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ML307 (ML-307)

生物&药学活性

物理化学性质&存储条件

参考文献

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