Chemical Structure : ML283
货号: PC-24071Not For Human Use, Lab Use Only.
ML283 is a potent, specific inhibitor of HCV non-structural protein 3 (NS3) helicase with IC50 of 2.6 uM (HCV genotype 1b), also inhibits DENV NS3-catalyzed RNA unwinding, also is a potent SARS-CoV-2 nsp13 helicase inhibitor.
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ML283 is a potent, specific inhibitor of HCV non-structural protein 3 (NS3) helicase with IC50 of 2.6 uM (HCV genotype 1b), also inhibits DENV NS3-catalyzed RNA unwinding, also is a potent SARS-CoV-2 nsp13 helicase inhibitor.
分子量 | 609.13 | |
分子式 | C28H21ClN4O4S3 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Sweeney NL, et al. ACS Infect Dis. 2015 Mar 13;1(3):140-148.
2. Li K, et al. Hepatitis C Virus NS3 Helicase Inhibitor Discovery.
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