ML 279 |CAS:1604821-55-7 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Immunology/Inflammation-Scavenger Receptor-ML 279

Chemical Structure : ML 279

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ML 279 (ML279)

货号: PC-62105Not For Human Use, Lab Use Only.

ML279 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 17 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ML279 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 17 nM.
ML279 stabilizes the interaction of HDL particles with SR-BI, and is non-toxic, plasma stable, and has improved solubility over alternative probe ML278.

物理化学性质&存储条件

分子量	468.55
分子式	C24H32N6O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-(2-(5-(benzo[d][1,3]dioxol-5-yl)-2H-tetrazol-2-yl)-N-cyclohexylacetamido)-N-cyclopentylpropanamide

参考文献

1. Dockendorff C, et al. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2594-8.

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ML 279 (ML279)

生物&药学活性

物理化学性质&存储条件

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ML 279 (ML279)

生物&药学活性

物理化学性质&存储条件

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