ML 278 |CAS:1604821-43-3 Probechem Biochemicals

Chemical Structure : ML 278

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ML 278 (ML278)

货号: PC-62104Not For Human Use, Lab Use Only.

ML278 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 6 nM.

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生物&药学活性

ML278 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 6 nM.
ML278 is a plasma-stable, noncytotoxic probe that exhibits moderate metabolic stability, thus displaying improved properties for in vitro and in vivo studies.
ML278 increases the binding of HDL to SR-BI.

物理化学性质&存储条件

分子量	453.513
分子式	C23H23N3O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3,5-dimethoxy-N-(4-(1-(2-methoxyacetyl)indolin-5-yl)thiazol-2-yl)benzamide

参考文献

1. Dockendorff C, et al. ACS Med Chem Lett. 2015 Feb 2;6(4):375-380.

ML 278 (ML278)

生物&药学活性

物理化学性质&存储条件

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ML 278 (ML278)

生物&药学活性

物理化学性质&存储条件

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