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首页-小分子抑制剂&激动剂-Others-Other Targets-ML257
ML257

Chemical Structure : ML257

CAS No.: 1362735-90-7

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ML257 (ABL303)

货号: PC-22333Not For Human Use, Lab Use Only.

ML257 (ABL303) is a selective inhibitor of α,β-hydrolase domain-containing 10 (ABHD10) with IC50 of 21 nM, >59-fold selectivity over 40+ other serine hydrolases.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ML257 (ABL303) is a selective inhibitor of α,β-hydrolase domain-containing 10 (ABHD10) with IC50 of 21 nM, >59-fold selectivity over 40+ other serine hydrolases.

物理化学性质&存储条件

分子量 362.43
分子式 C19H26N2O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

diisopropyl (R)-3-ethyl-4-oxo-3-(p-tolyl)-1,2-diazetidine-1,2-dicarboxylate

参考文献

1. Andrea M Zuhl, et al. J Am Chem Soc. 2012 Mar 21;134(11):5068-71.

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