ML2-SA2

Chemical Structure : ML2-SA2

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货号: PC-25086Not For Human Use, Lab Use Only.

ML2-SA2 is a selective, small-molecule TRPML2 channel agonist with EC50 of 6.4 uM, while inhibiting TRPML1 and TRPML3 with IC50 of 2.3 uM and 15.9 uM, respectively.

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生物&药学活性

ML2-SA2 is a selective, small-molecule TRPML2 channel agonist with EC50 of 6.4 uM, while inhibiting TRPML1 and TRPML3 with IC50 of 2.3 uM and 15.9 uM, respectively.
ML2-SA2 restores channel activity and vesicle trafficking in PI(3,5)P₂-insensitive cells.
ML2-SA2 reduces Golgi accumulation, and promotes peripheral vesicle dynamics.

物理化学性质&存储条件

分子量	435.61
分子式	C21H29N3O3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Thiophenesulfonamide, N-[(1R,2R)-2-[4-(2-methoxyphenyl)-1-piperazinyl]cyclohexyl]-, rel-

参考文献

1. Zi-Qi Gu, et al. Biomed Pharmacother. 2025 Jul 14:189:118350.

ML2-SA2

生物&药学活性

物理化学性质&存储条件

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ML2-SA2

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物理化学性质&存储条件

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