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首页-小分子抑制剂&激动剂-Others-Other Targets-ML181
ML181

Chemical Structure : ML181

CAS No.: 1415356-28-3

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ML181 (CYM50557)

货号: PC-38612Not For Human Use, Lab Use Only.

ML181 (CYM50557) is a potent and selective GPR7 (Neuropeptides B/W receptor 1, NPBW1) antagonist probe with IC50 of 270 nM for inhibition of NPW-induced GPR7 activation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    ML181 (CYM50557) is a potent and selective GPR7 (Neuropeptides B/W receptor 1, NPBWR1) antagonist probe with IC50 of 270 nM for inhibition of NPW-induced GPR7 activation.

    物理化学性质&存储条件

    分子量 356.806
    分子式 C19H17ClN2O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    5-Chloro-2-(3,5-dimethylphenyl)-4-(4-methoxyphenoxy)pyridazin-3-one

    参考文献

    1. Mariangela Urbano, et al. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7135-41.

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