ML145 | GPR35 inhibitor | Probechem Biochemicals

Chemical Structure : ML145

CAS No.: 1164500-72-4

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货号: PC-38607Not For Human Use, Lab Use Only.

ML145 (CID-2286812) is a selective GPR35 antagonist with IC50 of 20.1 nM, >1000-fold selectivity over GPR55.

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ML145 (CID-2286812) is a selective GPR35 antagonist with IC50 of 20.1 nM, >1000-fold selectivity over GPR55.

分子量	482.569
分子式	C24H22N2O5S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-hydroxy-4-[4-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2 enylidene]-4-oxo-2- sulfanylidene-1,3-thiazolidin-3-yl]butanoylamino] benzoic acid

1. Alkondon M, et al. Biochem Pharmacol. 2015 Feb 15;93(4):506-18.

2. Heynen-Genel S, et al. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.