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首页-小分子抑制剂&激动剂-Apoptosis-Caspase-ML132
ML132

Chemical Structure : ML132

CAS No.: 1230628-71-3

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ML132 (NCGC-00183434;CID-4462093)

货号: PC-63279Not For Human Use, Lab Use Only.

ML132 (NCGC-00183434, CID-4462093) is a highly potent, selective Caspase 1 inhibitor with IC50 of 0.023 nM, displays >1,000-fold selectivity over a panel of 9 caspases..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ML132 (NCGC-00183434, CID-4462093) is a highly potent, selective Caspase 1 inhibitor with IC50 of 0.023 nM, displays >1,000-fold selectivity over a panel of 9 caspases.

物理化学性质&存储条件

分子量 477.941
分子式 C22H28ClN5O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-3-((S)-1-((S)-2-(4-amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-cyanopropanoic acid

参考文献

1. Boxer MB, et al. A small molecule inhibitor of Caspase 1. Probe Reports from the NIH Molecular Libraries Program [Internet].

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