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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-NADPH Oxidase (NOX)-ML090
ML090

Chemical Structure : ML090

CAS No.: 531-46-4

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ML090 (CCG-44699;Fluoflavin;NSC 179821)

货号: PC-36153Not For Human Use, Lab Use Only.

ML090 (ML-090, CCG-44699, Fluoflavin, NSC 179821) is a potent, selecitve inhibitor of NADPH oxidase 1 (NOX1) with IC50 of 90 nM, displays no significant activities against NOX2, 3 and 4 (IC50>10 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ML090 (ML-090, CCG-44699, Fluoflavin, NSC 179821) is a potent, selecitve inhibitor of NADPH oxidase 1 (NOX1) with IC50 of 90 nM, displays no significant activities against NOX2, 3 and 4 (IC50>10 uM).

物理化学性质&存储条件

分子量 234.3
分子式 C14H10N4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5,12-dihydro-quinoxalino[2,3-b]quinoxaline

参考文献

1. Carmo LSD, et al. J Clin Invest. 2019 Mar 18;130. pii: 127682.

2. Smith RM, et al. Clin Exp Pharmacol Physiol. 2015 Aug;42(8):860-4.

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