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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-ML 086
ML 086

Chemical Structure : ML 086

CAS No.: 1177148-36-5

ML 086 (ML086;CID-1674999)

货号: PC-62547Not For Human Use, Lab Use Only.

ML 086 is a potent, specific inhibitor of phosphatase PHOSPHO1 with IC50 of 139 nM, with no activity against TNAP (IC50>100 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    ML 086 (ML086) is a potent, specific inhibitor of phosphatase PHOSPHO1 with IC50 of 139 nM, with no activity against TNAP (IC50>100 uM).
    ML 086 is a useful chemical tool to examine the functional role of this enzyme in skeletal mineralization and soft tissue ossification abnormalities.

    物理化学性质&存储条件

    分子量 298.36
    分子式 C16H14N2O2S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N,N-dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzamide

    参考文献

    1. Stonich D, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

    2. Bravo Y, et al. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4308-11.

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