ML-B01

Chemical Structure : ML-B01

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货号: PC-24887Not For Human Use, Lab Use Only.

ML-B01 is an ipatasertib analog and selective Akt inhibitor with IC50 of 2.0 nM and 136 nM for Akt1 and PKA respectively.

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ML-B01 is an ipatasertib analog and selective Akt inhibitor with IC50 of 2.0 nM and 136 nM for Akt1 and PKA respectively.

分子量	476.45
分子式	C24H31Cl2N5O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-1-(4-((5R,7R)-7-chloro-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-2-(4-chlorophenyl)-3-(isopropylamino)propan-1-one

1. Yan Wu, et al. Nat Chem Biol. 2025 Feb 11. doi: 10.1038/s41589-025-01846-y.