ML-241 |CAS:1346528-06-0 Probechem Biochemicals

Chemical Structure : ML-241

CAS No.: 1346528-06-0

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ML-241 (ML 241;ML241)

货号: PC-45718Not For Human Use, Lab Use Only.

ML241 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).

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25 mg	￥1580	In stock
50 mg	￥2480	In stock
100 mg	￥3980	In stock
200 mg		Get quote
1 g		Get quote

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生物&药学活性

ML241 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
ML241 blocks degradation of p97-dependent proteasome substrate with an IC50 of 3.5 uM.
ML241 induces caspases 3 and 7 and potently blocks proliferation in HCT15 and SW403 cells.

物理化学性质&存储条件

分子量	372.46
分子式	C23H24N4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-benzyl-2-(2,3-dihydro-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydroquinazolin-4-amine

参考文献

1. Chou TF, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

2. Chou TF, et al. ChemMedChem. 2013 Feb;8(2):297-312.

3. Fang CJ, et al. ChemMedChem. 2015 Jan;10(1):52-6.

ML-241 (ML 241;ML241)

生物&药学活性

物理化学性质&存储条件

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ML-241 (ML 241;ML241)

生物&药学活性

物理化学性质&存储条件

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