ML-184 |Cas:794572-10-4 Buy ML-184 from ProbeChem, Global Biochemicals Supplier

Chemical Structure : ML-184

CAS No.: 794572-10-4

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ML-184 (ML184)

货号: PC-70188Not For Human Use, Lab Use Only.

ML-184 (ML184) is a potent, selective GPR55 agonist with EC50 of 263 nM, >120-fold, 83-fold, and 57-fold selectivity against GPR35, CB1 and CB2.

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5 mg	￥2480	In stock
10 mg	￥3880	In stock
25 mg	￥5880	In stock
100 mg		Get quote

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生物&药学活性

ML-184 (ML184) is a potent, selective GPR55 agonist with EC50 of 263 nM, >120-fold, 83-fold, and 57-fold selectivity against GPR35, CB1 and CB2.
ML-184 shows activity in activating the downstream responses of ERK phosphorylation and PKC β II translocation.

物理化学性质&存储条件

分子量	470.6
分子式	C25H34N4O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-[[4-(2,3-Dimethylphenyl)-1-piperazinyl]carbonyl]-N,N-dimethyl-4-(1-pyrrolidinyl)benzenesulfonamide

参考文献

1. Heynen-Genel S, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

2. Lingerfelt MA, et al. Biochemistry. 2017 Jan 24;56(3):473-486.

ML-184 (ML184)

生物&药学活性

物理化学性质&存储条件

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ML-184 (ML184)

生物&药学活性

物理化学性质&存储条件

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