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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-IRE1-MKC9989
MKC9989

Chemical Structure : MKC9989

CAS No.: 1338934-20-5

MKC9989 (MKC 9989, MKC-9989)

货号: PC-62740Not For Human Use, Lab Use Only.

MKC9989 is a specific small molecule inhibitor of IRE1α Rnase (Kd=0.84 uM) with potency against the splicing of XBP1 mRNA (EC50=0.33 uM)..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MKC9989 is a specific small molecule inhibitor of IRE1α Rnase (Kd=0.84 uM) with potency against the splicing of XBP1 mRNA (EC50=0.33 uM).

物理化学性质&存储条件

分子量 336.34
分子式 C17H20O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7-hydroxy-6-methoxy-3-(2-(2-methoxyethoxy)ethyl)-4-methyl-2-oxo-2H-chromene-8-carbaldehyde

参考文献

1. Sanches M, et al. Nat Commun. 2014 Aug 28;5:4202.

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