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首页-小分子抑制剂&激动剂-GPCR-Cannabinoid Receptor-MK-9470
MK-9470

Chemical Structure : MK-9470

CAS No.: 945850-36-2

MK-9470 (MK9470)

货号: PC-62915Not For Human Use, Lab Use Only.

MK-9470 is a potent, selective cannabinoid CB1 receptor (CB1R) inverse agonist with IC50 of 0.7 nM, 18F MK-9470 has been developed for use in human brain imaging..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MK-9470 is a potent, selective cannabinoid CB1 receptor (CB1R) inverse agonist with IC50 of 0.7 nM, 18F MK-9470 has been developed for use in human brain imaging.

    物理化学性质&存储条件

    分子量 471.59
    分子式 C29H33N3O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-[(2S,3S)-3-(3-cyanophenyl)-4-(4-ethoxyphenyl)butan-2-yl]-2-methyl-2-[(5-methylpyridin-2-yl)oxy]propanamide

    参考文献

    1. Burns HD, et al. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9800-5.

    2. Van Laere K, et al. J Nucl Med. 2008 Mar;49(3):439-45.

    3. Gérard N, et al. J Mol Neurosci. 2010 Oct;42(2):162-7.

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