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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Calcium Channel -MK-8998
MK-8998

Chemical Structure : MK-8998

CAS No.: 953778-58-0

MK-8998 (Suvecaltamide, CX-8998, MK8998)

货号: PC-42314Not For Human Use, Lab Use Only.

MK-8998 (Suvecaltamide, CX-8998) is a potent and selective antagonist of the T-type calcium channel for the treatment of schizophrenia.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MK-8998 (Suvecaltamide, CX-8998) is a potent and selective antagonist of the T-type calcium channel for the treatment of schizophrenia.
MK-8998 does not block D2, 5HT2a, muscarinic, or histaminic receptors.
MK-8998 has the potential for a substantially improved side effect profile compared with currently available atypical antipsychotics.

物理化学性质&存储条件

分子量 380.4040296
分子式 C20H23F3N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzeneacetamide, 4-(1-methylethyl)-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)-2-pyridinyl]ethyl]-

参考文献

1. Egan MF, et al. Hum Psychopharmacol. 2013 Mar;28(2):124-33.

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