MK-8666 | GPR40 agonist | Probechem Biochemicals

Chemical Structure : MK-8666

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货号: PC-38228Not For Human Use, Lab Use Only.

MK-8666 is a potent, selective partial GPR40 agonist with EC50 of 0.9 nM, shows potential for the treatment of type 2 diabetes mellitus.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

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MK-8666 is a potent, selective partial GPR40 agonist with EC50 of 0.9 nM, shows potential for the treatment of type 2 diabetes mellitus.

分子量	521.628
分子式	C29H31NO6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(6R)-3-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)-[1,1'-biphenyl]-3-yl)methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid

1. Lu J, et al. Nat Struct Mol Biol. 2017 Jul;24(7):570-577.

2. Krug AW, et al. Clin Transl Sci. 2017 Sep;10(5):404-411.

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