Chemical Structure : MK-571 sodium salt
CAS No.: 115103-85-0
货号: PC-45775Not For Human Use, Lab Use Only.
MK-571 sodium is a potent and specific LTD4 receptor antagonist with Ki of 0.22 nM.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥980 | In stock | |
25 mg | ¥1580 | In stock | |
50 mg | ¥2580 | In stock | |
100 mg | Get quote |
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MK-571 sodium is a potent and specific LTD4 receptor antagonist with Ki of 0.22 nM.
MK-571 sodium effectively blocks LTD4 activation of recombinant human and mouse CysLT1 receptors.
MK-571 sodium also is an inhibitor of multidrug resistance protein-1 (MRP1) mediated transportorally active.
分子量 | 537.069 | |
分子式 | C26H26ClN2NaO3S2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
H2O: 50 mM in H2O (26.85 mg/mL, ultrasonic needed) |
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Chemical Name/SMILES |
Propanoic acid, 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-, sodium salt, (E)- (9CI) |
1. Gauthier JY, et al. J Med Chem. 1990 Oct;33(10):2841-5.
2. Vellenga E, et al. Br J Pharmacol. 1999 May;127(2):441-8.
3. Lynch K, et al. Nature. 1999 Jun 24;399(6738):789-93.
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