MK-5661 (MK5661) | Nav1.8 inhibitor | Probechem Biochemicals

Chemical Structure : MK-5661

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货号: PC-26880Not For Human Use, Lab Use Only.

MK-5661 (MK5661) is a potent, selective, and orally bioavailable NaV1.8 inhibitor with EC50 of 4.3 nM.

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MK-5661 (MK5661) is a potent, selective, and orally bioavailable NaV1.8 inhibitor with EC50 of 4.3 nM.

分子量	479.43
分子式	C18H18F5N5O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(4,4-difluoro-3-methylpiperidin-1-yl)-N-(2-sulfamoylpyridin-4-yl)-5-(trifluoromethyl)nicotinamide

1. Bungard CJ, et al. ACS Med Chem Lett. 2026 Apr 24;17(5):1189-1194.