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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-FAAH-MK-4409
MK-4409

Chemical Structure : MK-4409

CAS No.: 1207745-58-1

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MK-4409 (MK4409, MK 4409)

货号: PC-60219Not For Human Use, Lab Use Only.

MK-4409 is a potent and selective, brain penetrant FAAH inhibitor with IC50 of 11 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    MK-4409 is a potent and selective, brain penetrant FAAH inhibitor with IC50 of 11 nM.
    MK-4409 shows excellent efficacy in numerous preclinical models including the CFA and SNL pain models.

    物理化学性质&存储条件

    分子量 441.905
    分子式 C22H17FN3O2S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-[5-[5-(5-Chloropyridin-2-yl)sulfanyl-2-(4-fluorophenyl)-1,3-oxazol-4-yl]pyridin-2-yl]propan-2-ol

    参考文献

    1. Chobanian HR, et al. ACS Med Chem Lett. 2014 Apr 10;5(6):717-21.

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