MK-2894 sodium |CAS:1006036-88-9 Probechem Biochemicals

Chemical Structure : MK-2894 sodium

CAS No.: 1006036-88-9

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MK-2894 sodium (MK 2894 sodium;MK2894 sodium)

货号: PC-42573Not For Human Use, Lab Use Only.

MK-2894 sodium is a highly potent, selective, second generation prostaglandin E2 subtype 4 receptor (EP4) antagonist with Ki of 0.56 nM.

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10 mg	￥1880	In stock
25 mg	￥2880	In stock
50 mg	￥4580	In stock
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生物&药学活性

MK-2894 sodium is a highly potent, selective, second generation prostaglandin E2 subtype 4 receptor (EP4) antagonist with Ki of 0.56 nM.
MK-2894 displays >10,000-fold selectivity over EP2 receptors.
MK-2894 exhibits favorable pharmacokinetic profile and potent anti-inflammatory activity in animal models of pain/inflammation.

物理化学性质&存储条件

分子量	495.4891
分子式	C25H21F3NNaO3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzoic acid, 4-[1-[[[2,5-dimethyl-4-[[4-(trifluoromethyl)phenyl]methyl]-3-thienyl]carbonyl]amino]cyclopropyl]-, sodium salt (1:1)

参考文献

1. Blouin M, et al. J Med Chem. 2010 Mar 11;53(5):2227-38.

MK-2894 sodium (MK 2894 sodium;MK2894 sodium)

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MK-2894 sodium (MK 2894 sodium;MK2894 sodium)

生物&药学活性

物理化学性质&存储条件

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