Chemical Structure : MK-0773
CAS No.: 606101-58-0
货号: PC-42794Not For Human Use, Lab Use Only.
MK-0773 (PF-05314882) is a potent, selective androgen receptor modulator (SARM) with binding IC50 of 6.6 nM.
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MK-0773 (PF-05314882) is a potent, selective androgen receptor modulator (SARM) with binding IC50 of 6.6 nM.
MK-0773 (PF-05314882) displays no binding to other nuclear receptors ( GR, IC50> 2 uM) and 5α-reductase (IC50>10 uM).
MK-0773 (PF-05314882) improves muscle function while minimizing effects on other tissues.
分子量 | 479.5896 | |
分子式 | C27H34FN5O2 | |
外观性状 | Solid | |
储存条件 |
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|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
1H-Indeno[5,4-f]quinoline-7-carboxamide, 3-fluoro-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-N-(3H-imidazo[4,5-b]pyridin-2-ylmethyl)-1,4a,6a-trimethyl-2-oxo-, (4aS,4bS,6aS,7S,9aS,9bS,11aR)- |
1. Schmidt A, et al. J Biol Chem. 2010 May 28;285(22):17054-64.
2. Papanicolaou DA, et al. J Nutr Health Aging. 2013;17(6):533-43.
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