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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-11β-HSD-MK-0736
MK-0736

Chemical Structure : MK-0736

CAS No.: 719272-79-4

MK-0736 (MK0736)

货号: PC-21934Not For Human Use, Lab Use Only.

MK-0736 is a potent, selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor, shows favourable effect on glucose and lipid metabolism, weight reduction and adipokine levels.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MK-0736 is a potent, selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor, shows favourable effect on glucose and lipid metabolism, weight reduction and adipokine levels.

物理化学性质&存储条件

分子量 469.57
分子式 C23H30F3N3O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(4-(3-(Ethylsulfonyl)propyl)bicyclo[2.2.2]octan-1-yl)-4-methyl-5-(2-(trifluoromethyl)phenyl)-4H-1,2,4-triazole

参考文献

1. Shah S, et al. J Am Soc Hypertens. 2011 May-Jun;5(3):166-76.

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