MK-0674 |CAS:887781-62-6 Probechem Biochemicals

Chemical Structure : MK-0674

加入收藏

MK-0674 (MK0674, MK 0674)

货号: PC-62961Not For Human Use, Lab Use Only.

MK-0674 (MK 0674) is a potent, selective, reversible and orally active cathepsin K inhibitor with IC50 of 1 nM.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

MK-0674 (MK 0674) is a potent, selective, reversible and orally active cathepsin K inhibitor with IC50 of 1 nM.
MK-0674 exhibits long half-life in pre-clinical species, show stereoselective epimerization of the alcohol stereocenter via an oxidation/reduction cycle.

物理化学性质&存储条件

分子量	527.51
分子式	C26H27F6N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-(1-cyanocyclopropyl)-2-(((S)-1-(4'-((R)-2,2-difluoro-1-hydroxyethyl)-[1,1'-biphenyl]-4-yl)-2,2,2-trifluoroethyl)amino)-4-fluoro-4-methylpentanamide

参考文献

1. Isabel E, et al. Bioorg Med Chem Lett. 2010 Feb 1;20(3):887-92.

2. Murphy DJ, et al. J Am Chem Soc. 2015 Sep 9;137(35):11230-3.

MK-0674 (MK0674, MK 0674)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

MK-0674 (MK0674, MK 0674)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.