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首页-小分子抑制剂&激动剂-Others-Other Targets-MID-1
MID-1

Chemical Structure : MID-1

CAS No.: 312608-54-1

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MID-1 (ChemBridge5655896 )

货号: PC-35530Not For Human Use, Lab Use Only.

MID-1 (ChemBridge5655896) is a specific small molecule MG53-IRS-1 interaction disruptor (MID), but not MG53-FAK and-Cav-3 interaction.

规格 价格 库存 数量
5 mg ￥1280 In stock
10 mg ￥1980 In stock
25 mg ￥3280 In stock
50 mg ￥5280 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MID-1 (ChemBridge5655896) is a specific small molecule MG53-IRS-1 interaction disruptor (MID), but not MG53-FAK and-Cav-3 interaction.
MID-1 increases the IRS-1 protein level in C2C12 myotubes, abrogates MG53-induced IRS-1 ubiquitination and degradation.
MID-1 potentially sensitizes insulin signaling with an elevated level of IRS-1 in skeletal muscle, enhances C2C12 myogenesis.

物理化学性质&存储条件

分子量 293.30
分子式 C12H11N3O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-Ethoxy-N-(5-nitrothiazol-2-yl)benzamide

参考文献

1. Lee H, et al. J Biol Chem. 2016 Dec 23;291(52):26627-26635.

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