Chemical Structure : MI-1851
CAS No.: 2417283-44-2
货号: PC-26214Not For Human Use, Lab Use Only.
MI-1851 is a highly potent, peptidic mimetic inhibitor of furin with Ki of 10.1 pM, inhibits SARS-CoV-2 replication.
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MI-1851 is a highly potent, peptidic mimetic inhibitor of furin with Ki of 10.1 pM, inhibits SARS-CoV-2 replication.
| 分子量 | 767.90 | |
| 分子式 | C34H53N15O6 | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(S)-N-((S)-1-((4-carbamimidoylbenzyl)amino)-4-(guanidinooxy)-1-oxobutan-2-yl)-2-((S)-2-(2-(4-(guanidinomethyl)phenyl)acetamido)-4-(guanidinooxy)butanamido)-3,3-dimethylbutanamide |
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1. Bestle D, et al. Life Sci Alliance. 2020 Jul 23;3(9):e202000786.
2. Pászti-Gere E, et al. Biomed Pharmacother. 2022 Jul;151:113124.
3. Lange RW, et al. J Med Chem. 2025 Nov 30. doi: 10.1021/acs.jmedchem.5c02157.
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