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MI-1851

Chemical Structure : MI-1851

CAS No.: 2417283-44-2

MI-1851 (MI 1851, MI1851)

货号: PC-26214Not For Human Use, Lab Use Only.

MI-1851 is a highly potent, peptidic mimetic inhibitor of furin with Ki of 10.1 pM, inhibits SARS-CoV-2 replication.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MI-1851 is a highly potent, peptidic mimetic inhibitor of furin with Ki of 10.1 pM, inhibits SARS-CoV-2 replication.

物理化学性质&存储条件

分子量 767.90
分子式 C34H53N15O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N-((S)-1-((4-carbamimidoylbenzyl)amino)-4-(guanidinooxy)-1-oxobutan-2-yl)-2-((S)-2-(2-(4-(guanidinomethyl)phenyl)acetamido)-4-(guanidinooxy)butanamido)-3,3-dimethylbutanamide

参考文献

1. Bestle D, et al. Life Sci Alliance. 2020 Jul 23;3(9):e202000786.

2. Pászti-Gere E, et al. Biomed Pharmacother. 2022 Jul;151:113124.

3. Lange RW, et al. J Med Chem. 2025 Nov 30. doi: 10.1021/acs.jmedchem.5c02157.

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