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首页-小分子抑制剂&激动剂-Others-Other Targets-MI-1148
MI-1148

Chemical Structure : MI-1148

CAS No.: 1788032-54-1

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MI-1148 (MI1148, MI 1148)

货号: PC-27230Not For Human Use, Lab Use Only.

MI-1148 is a potent, peptidomimetic furin inhibitor with Ki of 5.5 pM, has significant protective effect against anthrax and diphtheria toxin, shows potent anti-infectious activity against H5N1 and H7N1 avian influenza viruses, West Nile and Dengue virus.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

MI-1148 is a potent, peptidomimetic furin inhibitor with Ki of 5.5 pM, has significant protective effect against anthrax and diphtheria toxin, shows potent anti-infectious activity against H5N1 and H7N1 avian influenza viruses, West Nile and Dengue virus.

物理化学性质&存储条件

分子量 763.95
分子式 C36H57N15O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-N-(4-carbamimidoylbenzyl)-5-guanidino-2-((S)-2-((S)-5-guanidino-2-(2-(4-(guanidinomethyl)phenyl)acetamido)pentanamido)-3,3-dimethylbutanamido)pentanamide

参考文献

1. Kornelia Hardes, et al. ChemMedChem. 2015 Jul;10(7):1218-31.

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