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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Guanylate Cyclase-MGV354
MGV354

Chemical Structure : MGV354

CAS No.: 1852495-86-3

MGV354 (MGV 354;MGV-354)

货号: PC-35119Not For Human Use, Lab Use Only.

MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.

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5 mg ¥1980 In stock
10 mg ¥2980 In stock
25 mg ¥4880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.

物理化学性质&存储条件

分子量 575.713
分子式 C35H37N5O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-1-(6-(3-((4-(1-(cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1H-inden-4-yl)pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic acid

参考文献

1. Prasanna G, et al. Invest Ophthalmol Vis Sci. 2018 Apr 1;59(5):1704-1716.

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